Spontaneous tumor lysis syndrome in small cell lung cancer

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Spontaneous Tumor Lysis Syndrome in Small Cell Lung Cancer

Tumor lysis syndrome (TLS) is a life-threatening oncologic complication caused by the lysis of a vast number of malignant cells resulting in metabolic derangements and organ dysfunction. TLS can occur spontaneously before initiation of any therapies often referred to as spontaneous tumor lysis syndrome (STLS), or shortly after the induction of chemotherapy, radiotherapy, or cytolytic antibody t...

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Spontaneous Tumor Lysis Syndrome in Small-Cell Lung Cancer: A Rare Complication

Tumor lysis syndrome (TLS) is a life-threatening condition which consists of a constellation of electrolyte imbalances, acute renal failure, seizure, and arrhythmias. It is most commonly seen with hematologic malignancies after the initiation of chemotherapy. However, it can also occur spontaneously, prior to treatment with cytotoxic agents. TLS has been rarely described with non-hematologic so...

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Spontaneous Tumor Lysis Syndrome in a Patient with Metastatic Small Cell Lung Cancer: A Case Report

Tumor lysis syndrome is an oncologic emergency that usually occurs after chemotherapy in patients with hematologic malignancies. Tumor lysis syndrome is rare in cases of solid tumors, especially when it occurs spontaneously. Herein, we present a case of spontaneous tumor lysis syndrome in a 55-year-old woman who presented with dyspnea and was found to have extensive metastatic small cell lung c...

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Spontaneous Tumor Lysis Syndrome in a Patient with Metastatic Small Cell Carcinoma of the Lung

Tumor Lysis Syndrome is characterized by an array of metabolic derangements such as hyperuricemia, hyperphosphatemia, hyperkalemia and hypocalcemia. The rapid release of cellular components into the cells after the lysis of malignant cells [1] leads to the above metabolic abnormalities. It is predominantly seen after the initiation of chemotherapy in hematological malignancies and is seldomly s...

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A 64-year-old male presented to hospital with breathlessness and weight loss. Ultrasound-guided biopsy of supraclavicular lymph node confirmed a diagnosis of small-cell lung cancer. The patient was started on Dexamethasone 8 mg twice daily for symptom control while awaiting urgent oncology assessment. Three days later he was admitted with acute kidney injury and worsening breathlessness. Bioche...

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ژورنال

عنوان ژورنال: Baylor University Medical Center Proceedings

سال: 2017

ISSN: 0899-8280,1525-3252

DOI: 10.1080/08998280.2017.1391042